Table 2

The effect of demographic characteristics on clinically relevant variation in function over two years

KOOS Activities of Daily Living

SF-36 Physical Function

Characteristic

Prevalence of clinically relevant change

Unadjusted for baseline values

Adjusted for baseline values

Prevalence of clinically relevant change

Unadjusted for baseline values

Adjusted for baseline value

N

%

OR

OR

95% CI

N

%

OR

OR

95% CI

Age

<46†

6/49

12

21/49

43

46–56

19/47

40

4.5

3.8

1.2–12.4

24/45

53

1.2

0.9

0.3–2.4

>56

13/47

28

2.5

1.8

0.5–6.2

23/46

50

1.3

0.5

0.2–1.4

Gender

men†

32/120

27

54/118

46

women

6/23

26

1.2

0.7

0.2–2.3

14/22

64

2.4

1.9

0.6–6.1

BMI (kg/m²)

<25†

9/61

15

21/60

35

25–29.9

22/64

34

1.4

2.0

0.5–3.9

39/63

62

3.2

2.4

1.0–5.7

≥30

7/16

44

1.4

1.8

0.3–6.3

6/15

40

1.2

0.1

0.2–0.9

KOOS = Knee injury and Osteoarthritis Outcome Score, OR = odds ratio, 95% CI = 95% confidence interval, BMI = body mass index.

* All risk factors listed are entered simultaneously in each model.

† Reference category.

Paradowski et al. Health and Quality of Life Outcomes 2005 3:59   doi:10.1186/1477-7525-3-59