|
CCQ scores in subgroups (Healthy, At Risk and COPD (Stage I-III)) |
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| COPD |
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| CCQ |
Healthy (ex)smokers |
At Risk (Stage 0) |
Mild (Stage I) |
Moderate A(Stage IIA) |
Moderate B (Stage IIB) |
Severe (Stage III) |
|
|
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| Symptom |
1.5a |
3.3b |
1.8a,c |
2.0c,d |
3.1b,d |
2.9,b,c |
| (0.3–3.5) |
(1.8–5.3) |
(0.5–5.0) |
(0.8–5.3) |
(0.8–4.5) |
(1.5–4.5) |
|
| Functional |
0.8a |
1.4b,c |
0.3a |
1.4b |
1.5b |
2.6c |
| state |
(0.0–3.8) |
(0.3–6.0) |
(0.0–2.5) |
(0.3–4.0) |
(0.5–4.8) |
(2.0–5.0) |
| Mental state |
0.0a |
0.0a,b |
0.0a |
0.0a,c |
1.0b |
0.5b,c |
| (0.0–3.0) |
(0.0–3.5) |
(0.0–1.0) |
(0.0–4.5) |
(0.0–5.0) |
(0.0–3.0) |
|
| Total |
0.8a |
2.0b,c |
1.0a,d |
1.3b,d |
1.9b,c |
2.5c |
| (0.1–3.3) |
(0.8–5.2) |
(0.2–2.5) |
(0.5–4.3) |
(0.9–4.7) |
(1.7–4.3) |
|
|
CCQ = Clinical COPD Questionnaire; range 0 – 6; 0 indicating best possible clinical control and 6 indicating worst possible clinical control. Medians not sharing a common superscript letter (a,b,c,d) are significant different at p < 0.05 after Mann-Whitney U test. Healthy (ex) smokers; normal spirometry, no chronic symptoms (cough, sputum production). COPD classification of COPD by severity according to the GOLD guidelines; Stage 0: normal spirometry, chronic symptoms (cough, sputum production); Stage I: FEV1/FVC < 70%, FEV1 ≥ 80 % predicted, with or without chronic symptoms (cough, sputum production, dyspnea); Stage IIA: FEV1/FVC < 70%, 50% ≥ FEV1 < 80 % predicted; Stage IIB: FEV1/FVC < 70%, 30% ≥ FEV1 < 50 % predicted; Stage III: FEV1/FVC < 70%, FEV1 < 30 % predicted or FEV1 < 50% predicted plus respiratory failure or clinical signs of right heart failure. | ||||||
van der Molen et al. Health and Quality of Life Outcomes 2003 1:13 doi:10.1186/1477-7525-1-13 |
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